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Clea headshot with Verzenio brand background

Clea Shearer

Entrepreneur, Mom, Verzenio Patient

Paid partnership with Eli Lilly and Company.

Clea Shearer

Entrepreneur, Mom, Verzenio Patient

Paid partnership with Eli Lilly and Company.

Thoughts From The Home Edit's Clea Shearer

"In 2022, when I was diagnosed with HR+, HER2– node-positive early breast cancer, I received an unexpected superpower: the power to look positively toward the future. With my family and care team by my side, I underwent a double mastectomy followed by months of chemotherapy and radiation. After active treatment, I started taking Verzenio with hormone therapy. I'm working with Lilly, the makers of Verzenio, to help other women like me learn what they can about early breast cancer and the importance of exploring treatment options. It's a mission and a journey that I personally will be on forever, and my plan is to make as big an impact as I can."

XO

clea signature in cursive

Learn more about Verzenio for Early Breast Cancer

Click here Right
Clea with a sign that reads 'peace out chemo'

Paid Sponsorship

Reducing her risk of recurrence

After she finished active treatment, Clea talked with her care team and family about what was next. Together, they decided taking Verzenio with hormone therapy was a great option for her. Knowing that by taking Verzenio her risk of recurrence may be reduced, Clea gained the peace of mind she needed to focus on what matters most – her family, friends, and The Home Edit community.

For women with HR+, HER2–, node-positive early breast cancer with a high chance of returning, as determined by your healthcare provider, Verzenio + hormone therapy showed a 35% reduction in the risk of cancer returning, compared with hormone therapy alone.

In a study, 85.5% of people taking Verzenio + hormone therapy were living without their cancer returning vs 78.6% taking hormone therapy alone. Data was assessed at 48 months; the study is ongoing to see if there is a survival benefit. Individual results may vary.

What makes Verzenio different? Right

SELECT SAFETY INFORMATION

Warnings - Verzenio may cause serious side effects, including:

Diarrhea is common with Verzenio, may sometimes be severe and may cause dehydration or infection. The most common time to develop diarrhea is during the first month of Verzenio treatment. If you develop diarrhea during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, stop your treatment, or decrease your dose. If you have any loose stools, start taking an antidiarrheal medicine (such as loperamide), drink more fluids, and tell your healthcare provider right away.

Clea pictured with her husband, daughter, and son posing for a picture outside

Moving forward with Verzenio

Following her diagnosis, Clea found that her gratitude and appreciation for life reached new levels. Now, Clea eagerly anticipates the future, with thrilling projects for The Home Edit on the horizon and many joyful family moments to come. She is also looking forward to dedicating time to one important mission: working in partnership with Lilly and Verzenio to raise awareness for HR+, HER2– high-risk early breast cancer. This partnership will encourage more people to talk with their doctors about recurrence risk factors and available treatment options.

Talk to your doctor about whether Verzenio is right for you

Click here Right

Clea, a breast cancer patient undergoing treatment with Verzenio, shares insights from her experience alongside oncologist Dr. Ben Ho Park.

Clea learns what “high-risk” early breast cancer means

For HR+, HER2–, node-positive early breast cancer with a high chance of returning, as determined by your healthcare provider.

"So even though the words ”high risk” are scary, I understood them thanks to you." – Clea Shearer

Each person’s experience is unique.

Dr. Ben Ho Park explain what High-Risk means

00:30

Clea
Dr. Ben, how do you explain high risk to early breast cancer patients like me?

00:34

Dr. Park
So high risk is going to scare a lot of patients, because that means that the likelihood of recurrence is going to be higher, obviously, than lower risk. But then I try to follow up with that. Meaning, well, this is why we're going to prescribe more therapies.

00:46

Clea
You made me feel much better by talking me through different available treatment options and the things that I could do to potentially reduce my risk of recurrence. So even though the words high risk are scary, I understood them thanks to you, thanks to you explaining it, and I felt really good about moving forward on a path to do everything possible to reduce my risk.

01:13

Dr. Park
I think it really behooves patients to be their advocates, their own advocates. Talk to other patients, talk to other physicians to get second and even third opinions and really start formulating, hey, why are we doing this part of the therapy? Because I actually think it's no longer a passive game for patients just to do whatever the doctors say.

01:34

Dr. Park
There has to be reasoning behind it. And I think that's what empowers patients to really go and feel comfortable with the therapies that their doctors have prescribed.

01:42

Clea
You and my entire care team, you listen to every single concern I had answered every single question, made me feel really confident about my treatment, made me feel really confident about taking Verzenio and doing all the things I could possibly do to potentially reduce my risk of recurrence.

02:24

VO:

INDICATION AND SAFETY SUMMARY

Verzenio is used to treat certain types of breast cancer known as HR positive, HER 2 negative (hormone receptor positive/human epidermal growth factor receptor 2 negative) breast cancer.

It is a medicine you can take if:

  • You have node-positive early breast cancer that has a high risk of coming back as determined by your healthcare provider. Verzenio is given along with hormonal therapy to women and men.

It is not known if Verzenio is safe and effective in children.

Warnings - Verzenio may cause serious side effects, including:

Diarrhea is common with Verzenio, may sometimes be severe and may cause dehydration or infection. The most common time to develop diarrhea is during the first month of Verzenio treatment. If you develop diarrhea during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, stop your treatment, or decrease your dose.

If you have any loose stools, start taking an antidiarrheal medicine (such as loperamide), drink more fluids, and tell your healthcare provider right away.

Low white blood cell counts (neutropenia) are common with Verzenio and may cause serious infections that can lead to death. Your healthcare provider should check your white blood cell counts before and during treatment. If you develop low white blood cell counts during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose, or wait before starting your next month of treatment. Tell your healthcare provider right away if you have signs and symptoms of low white blood cell counts or infections, such as fever and chills.

Verzenio may cause severe or life-threatening inflammation (swelling) of the lungs during treatment that can lead to death. If you develop lung problems during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose, or stop your treatment. Tell your healthcare provider right away if you have any new or worsening symptoms, including:

  • Trouble breathing or shortness of breath
  • Cough with or without mucus
  • Chest pain

Verzenio can cause serious liver problems. Your healthcare provider should do blood tests to check your liver before and during treatment. If you develop liver problems during treatment with Verzenio, your health care provider may reduce your dose or stop your treatment. Tell your healthcare provider right away if you have any of the following signs or symptoms of liver problems:

  • Feeling very tired
  • Pain on the upper right side of your stomach area (abdomen)
  • Loss of appetite
  • Bleeding or bruising more easily than normal

Verzenio may cause blood clots in your veins, or in the arteries of your lungs. Verzenio may cause serious blood clots that have led to death. If you develop blood clots during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it. Tell your healthcare provider right away if you have any of the following signs and symptoms of a blood clot:

  • Pain or swelling in your arms or legs
  • Shortness of breath
  • Chest pain
  • Fast breathing

Verzenio can harm your unborn baby. Use effective birth control (contraception) during treatment and for 3 weeks after the last dose of Verzenio and do not breastfeed during treatment with Verzenio and for at least 3 weeks after your last dose. Verzenio may affect the ability of males to father a child.

Common side effects

The most common side effects of Verzenio include:

  • Nausea
  • Infections
  • Low red blood cell counts (anemia)
  • Decreased appetite
  • Headache
  • Hair thinning or hair loss (alopecia)
  • Abdominal pain
  • Tiredness
  • Low white blood cell counts (leukopenia)
  • Vomiting
  • Low platelet counts (thrombocytopenia)

These are not all the possible side effects of Verzenio.

Tell your healthcare provider if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using

Before you use Verzenio, tell your healthcare provider about all your medical conditions, including:

  • If you have fever, chills, or other signs of infection.
  • If you have a history of blood clots in your veins.
  • Have lung or breathing problems.
  • Have liver or kidney problems.
  • If you are pregnant, plan to become pregnant, or are breastfeeding.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take a medicine that contains ketoconazole.

How to take

  • Take Verzenio exactly as your healthcare provider tells you.
  • Your healthcare provider may change your dose if needed. Do not stop taking Verzenio or change the dose without talking to your healthcare provider.
  • Verzenio may be taken with or without food.
  • Swallow Verzenio tablets whole. Do not chew, crush, or split the tablets before swallowing. Do not take Verzenio tablets if they are broken, cracked, or damaged.
  • Take your doses of Verzenio at about the same time every day.
  • If you vomit or miss a dose of Verzenio, take your next dose at your regular time. Do not take 2 doses at the same time to make up for the missed dose.

What to avoid during treatment

  • Avoid taking ketoconazole during treatment with Verzenio. Tell your healthcare provider if you take a medicine that contains ketoconazole
  • Avoid grapefruit and products that contain grapefruit during treatment with Verzenio. Grapefruit may increase the amount of Verzenio in your blood

Learn more

Verzenio is a prescription medicine. For more information, call 1-800-545-5979 or go to verzenio.com.

This summary provides basic information about Verzenio but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Verzenio and how to take it. Your healthcare provider is the best person to help you decide if Verzenio is right for you.

Verzenio is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates.

CMAT-03521 01/2026 ©Lilly USA, LLC 2026. All rights reserved.

Clea, a current Verzenio breast cancer patient, shares insights around her experience along with oncologist, Dr. Ben Ho Park.

Clea talks about starting treatment

For HR+, HER2–, node-positive early breast cancer with a high chance of returning, as determined by your healthcare provider.

"When I was first diagnosed, every decision felt overwhelming... And you walked me through every step. Surgery, chemo then Verzenio." – Clea Shearer

Each person’s experience is unique.

Clea and Dr. Park talk about Starting Verzenio

00:29

Clea
When I was first diagnosed, every decision felt overwhelming.

00:32

Dr. Park
Cancer disrupts your entire life. That's why, from our first conversation, I wanted you to know you weren't alone.

00:38

Clea
And you walked me through every step. Surgery, chemo then Verzenio.

00:43

Dr. Park
Because you didn't have just HR+, HER2-, node-positive, early breast cancer. You also had a pretty high risk of that cancer coming back. So we wanted to do everything we could. What helped you feel ready to move forward with taking Verzenio?

00:57

Clea
You helped me move forward. And I think we were both in complete agreement that I'm young and it's time to do every single thing I possibly can do to reduce my risk of recurrence.

01:07

Dr Park
I wanted to make sure you felt confident and informed about the choices we made together. The data show that for high-risk disease, Verzenio plus hormone therapy could reduce some of that risk of recurrence.

01:45

Clea
I felt empowered to live my life, which is something I did not expect at the beginning of my journey. I feel like I can move forward knowing Verzenio may be helping to reduce my risk of recurrence. It's made such a difference having an oncologist like you who’s always there to answer my questions.

02:02

Dr Park
That's what I'm here for.

02:07

VO:

INDICATION AND SAFETY SUMMARY

Verzenio is used to treat certain types of breast cancer known as HR positive, HER 2 negative (hormone receptor positive/human epidermal growth factor receptor 2 negative) breast cancer.

It is a medicine you can take if:

  • You have node-positive early breast cancer that has a high risk of coming back as determined by your healthcare provider. Verzenio is given along with hormonal therapy to women and men.

It is not known if Verzenio is safe and effective in children.

Warnings - Verzenio may cause serious side effects, including:

Diarrhea is common with Verzenio, may sometimes be severe and may cause dehydration or infection. The most common time to develop diarrhea is during the first month of Verzenio treatment. If you develop diarrhea during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, stop your treatment, or decrease your dose.

If you have any loose stools, start taking an antidiarrheal medicine (such as loperamide), drink more fluids, and tell your healthcare provider right away.

Low white blood cell counts (neutropenia) are common with Verzenio and may cause serious infections that can lead to death. Your healthcare provider should check your white blood cell counts before and during treatment. If you develop low white blood cell counts during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose, or wait before starting your next month of treatment. Tell your healthcare provider right away if you have signs and symptoms of low white blood cell counts or infections, such as fever and chills.

Verzenio may cause severe or life-threatening inflammation (swelling) of the lungs during treatment that can lead to death. If you develop lung problems during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose, or stop your treatment. Tell your healthcare provider right away if you have any new or worsening symptoms, including:

  • Trouble breathing or shortness of breath
  • Cough with or without mucus
  • Chest pain

Verzenio can cause serious liver problems. Your healthcare provider should do blood tests to check your liver before and during treatment. If you develop liver problems during treatment with Verzenio, your health care provider may reduce your dose or stop your treatment. Tell your healthcare provider right away if you have any of the following signs or symptoms of liver problems:

  • Feeling very tired
  • Pain on the upper right side of your stomach area (abdomen)
  • Loss of appetite
  • Bleeding or bruising more easily than normal

Verzenio may cause blood clots in your veins, or in the arteries of your lungs. Verzenio may cause serious blood clots that have led to death. If you develop blood clots during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it. Tell your healthcare provider right away if you have any of the following signs and symptoms of a blood clot:

  • Pain or swelling in your arms or legs
  • Shortness of breath
  • Chest pain
  • Fast breathing

Verzenio can harm your unborn baby. Use effective birth control (contraception) during treatment and for 3 weeks after the last dose of Verzenio and do not breastfeed during treatment with Verzenio and for at least 3 weeks after your last dose. Verzenio may affect the ability of males to father a child.

Common side effects

The most common side effects of Verzenio include:

  • Nausea
  • Infections
  • Low red blood cell counts (anemia)
  • Decreased appetite
  • Headache
  • Hair thinning or hair loss (alopecia)
  • Abdominal pain
  • Tiredness
  • Low white blood cell counts (leukopenia)
  • Vomiting
  • Low platelet counts (thrombocytopenia)

These are not all the possible side effects of Verzenio.

Tell your healthcare provider if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using

Before you use Verzenio, tell your healthcare provider about all your medical conditions, including:

  • If you have fever, chills, or other signs of infection.
  • If you have a history of blood clots in your veins.
  • Have lung or breathing problems.
  • Have liver or kidney problems.
  • If you are pregnant, plan to become pregnant, or are breastfeeding.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take a medicine that contains ketoconazole.

How to take

  • Take Verzenio exactly as your healthcare provider tells you.
  • Your healthcare provider may change your dose if needed. Do not stop taking Verzenio or change the dose without talking to your healthcare provider.
  • Verzenio may be taken with or without food.
  • Swallow Verzenio tablets whole. Do not chew, crush, or split the tablets before swallowing. Do not take Verzenio tablets if they are broken, cracked, or damaged.
  • Take your doses of Verzenio at about the same time every day.
  • If you vomit or miss a dose of Verzenio, take your next dose at your regular time. Do not take 2 doses at the same time to make up for the missed dose.

What to avoid during treatment

  • Avoid taking ketoconazole during treatment with Verzenio. Tell your healthcare provider if you take a medicine that contains ketoconazole
  • Avoid grapefruit and products that contain grapefruit during treatment with Verzenio. Grapefruit may increase the amount of Verzenio in your blood

Learn more

Verzenio is a prescription medicine. For more information, call 1-800-545-5979 or go to verzenio.com.

This summary provides basic information about Verzenio but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Verzenio and how to take it. Your healthcare provider is the best person to help you decide if Verzenio is right for you.

Verzenio is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates.

CMAT-03522 01/2026 ©Lilly USA, LLC 2026. All rights reserved.

Explore Clea’s treatment journey with Verzenio and hear additional context from her oncologist, Dr. Ben Ho Park.

Clea talks about her experience with side effects

For HR+, HER2–, node-positive early breast cancer with a high chance of returning, as determined by your healthcare provider.

"You always have to keep an open line of communication with your doctor, and if anything feels like it's not going to be a sustainable solution you need to speak up and advocate for yourself." – Clea Shearer

Patient experiences vary.

Clea and Dr. Park talk about Managing the Side Effects of Verzenio

00:30

Dr. Park
So, you finished active treatment for HR+, HER2-, node-positive early breast cancer with a high chance of returning. Then you started Verzenio plus hormone therapy. What were those first few weeks like?

00:40

Clea
The first few weeks of taking Verzenio, I definitely had some side effects that you had warned me about and that I was a little concerned about. I talked to you and we, you know, talked through the different side effects that I was experiencing and tried to figure out how to mitigate those side effects.

00:54

Dr Park
I always make it a point, and you and I discussed this at the beginning. Any side effects you have I want to know about because I don't want patients to suffer through their treatments. Making sure that you're comfortable is part of what makes treatment successful.

01:06

Clea
While I felt okay, I felt like it was worth talking to you about. I told you right away and you said, let's try a dose adjustment to see if that helps. So you reduced my dose from 150mg starting dose. It made a huge difference for me. I'm so glad we could find a solution together.

01:22

Dr. Park
What would you say to someone who's nervous about starting Verzenio because of the possibility of side effects?

01:27

Clea
You always have to keep an open line of communication with your doctor, and if anything feels like it's not going to be a sustainable solution, you need to speak up and advocate for yourself. I think that the most important thing is to do everything possible to keep cancer from coming back.

01:45

VO:

INDICATION AND SAFETY SUMMARY

Verzenio is used to treat certain types of breast cancer known as HR positive, HER 2 negative (hormone receptor positive/human epidermal growth factor receptor 2 negative) breast cancer.

It is a medicine you can take if:

  • You have node-positive early breast cancer that has a high risk of coming back as determined by your healthcare provider. Verzenio is given along with hormonal therapy to women and men.

It is not known if Verzenio is safe and effective in children.

Warnings - Verzenio may cause serious side effects, including:

Diarrhea is common with Verzenio, may sometimes be severe and may cause dehydration or infection. The most common time to develop diarrhea is during the first month of Verzenio treatment. If you develop diarrhea during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, stop your treatment, or decrease your dose.

If you have any loose stools, start taking an antidiarrheal medicine (such as loperamide), drink more fluids, and tell your healthcare provider right away.

Low white blood cell counts (neutropenia) are common with Verzenio and may cause serious infections that can lead to death. Your healthcare provider should check your white blood cell counts before and during treatment. If you develop low white blood cell counts during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose, or wait before starting your next month of treatment. Tell your healthcare provider right away if you have signs and symptoms of low white blood cell counts or infections, such as fever and chills.

Verzenio may cause severe or life-threatening inflammation (swelling) of the lungs during treatment that can lead to death. If you develop lung problems during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose, or stop your treatment. Tell your healthcare provider right away if you have any new or worsening symptoms, including:

  • Trouble breathing or shortness of breath
  • Cough with or without mucus
  • Chest pain

Verzenio can cause serious liver problems. Your healthcare provider should do blood tests to check your liver before and during treatment. If you develop liver problems during treatment with Verzenio, your health care provider may reduce your dose or stop your treatment. Tell your healthcare provider right away if you have any of the following signs or symptoms of liver problems:

  • Feeling very tired
  • Pain on the upper right side of your stomach area (abdomen)
  • Loss of appetite
  • Bleeding or bruising more easily than normal

Verzenio may cause blood clots in your veins, or in the arteries of your lungs. Verzenio may cause serious blood clots that have led to death. If you develop blood clots during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it. Tell your healthcare provider right away if you have any of the following signs and symptoms of a blood clot:

  • Pain or swelling in your arms or legs
  • Shortness of breath
  • Chest pain
  • Fast breathing

Verzenio can harm your unborn baby. Use effective birth control (contraception) during treatment and for 3 weeks after the last dose of Verzenio and do not breastfeed during treatment with Verzenio and for at least 3 weeks after your last dose. Verzenio may affect the ability of males to father a child.

Common side effects

The most common side effects of Verzenio include:

  • Nausea
  • Infections
  • Low red blood cell counts (anemia)
  • Decreased appetite
  • Headache
  • Hair thinning or hair loss (alopecia)
  • Abdominal pain
  • Tiredness
  • Low white blood cell counts (leukopenia)
  • Vomiting
  • Low platelet counts (thrombocytopenia)

These are not all the possible side effects of Verzenio.

Tell your healthcare provider if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using

Before you use Verzenio, tell your healthcare provider about all your medical conditions, including:

  • If you have fever, chills, or other signs of infection.
  • If you have a history of blood clots in your veins.
  • Have lung or breathing problems.
  • Have liver or kidney problems.
  • If you are pregnant, plan to become pregnant, or are breastfeeding.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take a medicine that contains ketoconazole.

How to take

  • Take Verzenio exactly as your healthcare provider tells you.
  • Your healthcare provider may change your dose if needed. Do not stop taking Verzenio or change the dose without talking to your healthcare provider.
  • Verzenio may be taken with or without food.
  • Swallow Verzenio tablets whole. Do not chew, crush, or split the tablets before swallowing. Do not take Verzenio tablets if they are broken, cracked, or damaged.
  • Take your doses of Verzenio at about the same time every day.
  • If you vomit or miss a dose of Verzenio, take your next dose at your regular time. Do not take 2 doses at the same time to make up for the missed dose.

What to avoid during treatment

  • Avoid taking ketoconazole during treatment with Verzenio. Tell your healthcare provider if you take a medicine that contains ketoconazole
  • Avoid grapefruit and products that contain grapefruit during treatment with Verzenio. Grapefruit may increase the amount of Verzenio in your blood

Learn more

Verzenio is a prescription medicine. For more information, call 1-800-545-5979 or go to verzenio.com.

This summary provides basic information about Verzenio but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Verzenio and how to take it. Your healthcare provider is the best person to help you decide if Verzenio is right for you.

Verzenio is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates.

CMAT-03523 01/2026 ©Lilly USA, LLC 2026. All rights reserved.

Clea standing together with friend

About The Home Edit's Clea Shearer

Clea Shearer is a Nashville-based home organizing expert and Co-Founder of The Home Edit alongside her best friend Joanna Teplin. The Home Edit was founded with the goal of reinventing traditional organizing and merging it with design. Since then, it has grown into a global media and organization company with a social following of over 9 million people and organizing teams in 7 cities across the country. The Home Edit has become a household name with three New York Times' bestselling books, an Emmy®-nominated Netflix® show, Get Organized with The Home Edit, and a successful line of organizational products sold in stores in over 31 countries. Their work continues to reach a wide audience with the upcoming relaunch of ABC's Extreme Makeover: Home Edition. In 2022, Clea was diagnosed with breast cancer after finding a lump in her breast during a self-exam. After a double mastectomy and active treatment, Clea began taking Verzenio with hormone therapy. Inspired by her own cancer journey, Clea has made it her mission to help raise awareness around breast cancer to help women like her feel less alone.

SAFETY SUMMARY

Warnings - Verzenio may cause serious side effects, including: Diarrhea is common with Verzenio, may sometimes be severe and may cause dehydration or infection. The most common time to develop diarrhea is during the first month of Verzenio treatment. If you develop diarrhea during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, stop your treatment, or decrease your dose.
If you have any loose stools, start taking an antidiarrheal medicine (such as loperamide), drink more fluids, and tell your healthcare provider right away.

Low white blood cell counts (neutropenia) are common with Verzenio and may cause serious infections that can lead to death. Your healthcare provider should check your white blood cell counts before and during treatment. If you develop low white blood cell counts during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose, or wait before starting your next month of treatment. Tell your healthcare provider right away if you have signs and symptoms of low white blood cell counts or infections, such as fever and chills.

Verzenio may cause severe or life-threatening inflammation (swelling) of the lungs during treatment that can lead to death. If you develop lung problems during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose, or stop your treatment. Tell your healthcare provider right away if you have any new or worsening symptoms, including:

  • Trouble breathing or shortness of breath
  • Cough with or without mucus
  • Chest pain

Verzenio can cause serious liver problems. Your healthcare provider should do blood tests to check your liver before and during treatment. If you develop liver problems during treatment with Verzenio, your health care provider may reduce your dose or stop your treatment. Tell your healthcare provider right away if you have any of the following signs or symptoms of liver problems:

  • Feeling very tired
  • Pain on the upper right side of your stomach area (abdomen)
  • Loss of appetite
  • Bleeding or bruising more easily than normal

Verzenio may cause blood clots in your veins, or in the arteries of your lungs. Verzenio may cause serious blood clots that have led to death. If you develop blood clots during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it. Tell your healthcare provider right away if you have any of the following signs and symptoms of a blood clot:

  • Pain or swelling in your arms or legs
  • Shortness of breath
  • Chest pain
  • Fast breathing
  • Fast heart rate

Verzenio can harm your unborn baby. Use effective birth control (contraception) during treatment and for 3 weeks after the last dose of Verzenio and do not breastfeed during treatment with Verzenio and for at least 3 weeks after your last dose. Verzenio may affect the ability of males to father a child.

Common side effects

The most common side effects of Verzenio include:

  • Nausea
  • Infections
  • Low red blood cell counts (anemia)
  • Decreased appetite
  • Headache
  • Hair thinning or hair loss (alopecia)
  • Abdominal pain
  • Tiredness
  • Low white blood cell counts (leukopenia)
  • Vomiting
  • Low platelet counts (thrombocytopenia)

These are not all the possible side effects of Verzenio.

Tell your healthcare provider if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using

Before you use Verzenio, tell your healthcare provider about all your medical conditions, including:

  • If you have fever, chills, or other signs of infection.
  • If you have a history of blood clots in your veins.
  • Have lung or breathing problems.
  • Have liver or kidney problems.
  • If you are pregnant, plan to become pregnant, or are breastfeeding.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take a medicine that contains ketoconazole.

How to take

  • Take Verzenio exactly as your healthcare provider tells you.
  • Your healthcare provider may change your dose if needed. Do not stop taking Verzenio or change the dose without talking to your healthcare provider.
  • Verzenio may be taken with or without food.
  • Swallow Verzenio tablets whole. Do not chew, crush, or split the tablets before swallowing. Do not take Verzenio tablets if they are broken, cracked, or damaged.
  • Take your doses of Verzenio at about the same time every day.
  • If you vomit or miss a dose of Verzenio, take your next dose at your regular time. Do not take 2 doses at the same time to make up for the missed dose.

What to avoid during treatment

  • Avoid taking ketoconazole during treatment with Verzenio. Tell your healthcare provider if you take a medicine that contains ketoconazole
  • Avoid grapefruit and products that contain grapefruit during treatment with Verzenio. Grapefruit may increase the amount of Verzenio in your blood

Learn more

Verzenio is a prescription medicine. For more information, call 1-800-545-5979.

This summary provides basic information about Verzenio but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Verzenio and how to take it. Your healthcare provider is the best person to help you decide if Verzenio is right for you.

AL CON BS 03MAR2023

Verzenio® is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates.

INDICATIONS

Verzenio® (ver-ZEN-ee-oh) is used to treat certain types of breast cancer known as HR+/HER2– (hormone receptor positive/human epidermal growth factor receptor 2 negative) breast cancer.
It is a medicine you can take if:

  • You have node-positive early breast cancer that has a high risk of coming back as determined by your healthcare provider. Verzenio is given along with hormonal therapy to women and men.
  • Or, the cancer has spread to other parts of the body (metastasized). If you are female or male, then Verzenio is given with an aromatase inhibitor as initial endocrine-based therapy. If you are a female or male, and the cancer has gotten worse after hormonal therapy, then Verzenio is given with fulvestrant. If you are female or male and the cancer has gotten worse after both hormonal therapy and chemotherapy, then Verzenio is given by itself.

It is not known if Verzenio is safe and effective in children.

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To speak to customer support:
Call (800) 545-5979

This site is intended for US residents aged 18 and older.

PP-AL-US-4878 04/2026 ©Lilly USA, LLC 2026. All rights reserved.

Verzenio® is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates. Lilly Support Services™, Companion in Care™, and Verzenio Vision™ are trademarks owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates.

Imodium® is a registered trademark of Johnson & Johnson.

Other product/company names mentioned herein are the trademarks of their respective owners.

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