0:00
Caption: Verzenio logo, Verzenio is a prescription medicine used in combination with endocrine (hormone) therapy (tamoxifen or an aromatase inhibitor) to treat adults with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2–), node-positive early breast cancer with a high risk of coming back as determined by your healthcare provider.
It is not known if it's safe and effective in children.
Please see Indication and Safety Summary at the end of this video.
Caption: Susan is a real Verzenio patient. Individual results may vary. Talk to your doctor to see if Verzenio is right for you.
00:19
[Susan walks into a kitchen, she smiles]
VO: I'm Susan. I'm a wife. I'm a mother.
00:23
[Susan’s husband walks in, kisses her on the cheek]
VO: My husband, Jamie, and I've been married. We celebrated 30 years last year.
00:27
[Susan’s daughter walks into the kitchen, chats with her. Her son washes his hands at the sink]
VO: I have two grown children, Nicole and Logan.
00:31
[Close Ups of food prep, the two women prepare sushi]
VO: Nicole and I, we love to host. We love to have our friends over. We will cook and make things for them.
00:37
[Susan hugs her friends as they enter house]
VO: And they mean the world to me. My friends are my support system. They are always there for me. Through good times, through bad times.
00:45
[Susan talks to camera]
VO: My friends are like my family. There's like nothing I wouldn't do for them.
00:49
[The group of women talk in the kitchen]
VO: When Mimi found out that she needed a kidney donor, we all wanted to be tested.
00:53
[Susan talks to camera]
VO: And so we went through the testing to see if we'd be a match. And I scheduled my mammogram to get started.
01:03
[The group of women sit at a dining room table and continue to talk]
VO: I remember so vividly, Mimi, when we were just talking about it and getting tested. And I do remember that just thinking that I just had that feeling, you know, that there was going to be something that you're going to save my life and me trying to save your life.
01:14
[Susan sits and reflects]
VO: I was diagnosed with HR positive,
01:17
[Susan talks to camera]
VO: HER2 negative, node positive, early breast cancer.
01:22
[Susan sits, reflects, and talks to camera]
VO: After my diagnosis, it seemed like things move fast. We scheduled a breast MRI and they found that there were four suspicious masses. So then it became from a simple lumpectomy so my doctor, and I discussed that the double mastectomy was going to be the next steps.
01:40
[Susan drinks tea]
VO: During active treatment. It was hard.
01:42
[Susan talks to camera]
VO: I felt like at times things are out of control and I'm somebody that likes to have a plan.
01:49
[Archival photo: Susan poses at the hospital, with staff]
VO: I felt like after my surgery and after my active treatment, in my mind I was like, what's next?
01:56
[Susan talks to camera]
VO: Is there a next step? Is it all done? And I had a worry about, you know,
Caption: Verzenio + hormone therapy showed a 35% reduction in the risk of cancer returning, compared with hormone therapy alone. In a study, 85.5% of people taking Verzenio+ hormone therapy were alive without their cancer returning vs 78.6% taking hormone therapy alone. Data was assessed at 48 months; the study is ongoing to see if there is a survival benefit.
02:01
[Susan holds a teacup, and reflects]
VO Susan: the cancer coming back reoccurring. And so when my doctor told me about Verzenio and hormone therapy
02:04
[Susan talks to camera]
VO: And the possibility of reducing the risk, it made me feel calm. It made me feel confident in the next steps,
Caption: Warnings - Verzenio may cause serious side effects, including: Diarrhea is common with Verzenio, may sometimes be severe and may cause dehydration or infection. The most common time to develop diarrhea is during the first month of Verzenio treatment.
02:13
[The group of women sit around a fire pit at night, talking]
VO: Taking Verzenio gave me confidence because I was taking something specifically for my type of cancer,
Caption: If you develop diarrhea during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, stop your treatment, or decrease your dose.
02:19
VO: And that made me feel even more confident that I was doing the right thing. I was doing all that I can do.
02:23
[Susan talks to camera]
VO: I felt like my doctor was very good at setting expectations.
Caption: If you have any loose stools, start taking an antidiarrheal medicine (such as loperamide), drink more fluids, and tell your healthcare provider right away.
02:26
[Susan and her daughter prepare food in the kitchen. Her son and husband join]
VO: She was very good at preparing me to help manage the side effects.
Caption: The most common side effects of taking Verzenio + hormone therapy: Diarrhea, Low white blood cell counts (neutropenia, leukopemia), Nausea, Infections, Low red blood cell counts (anemia), Decreased appetite, Headache, Hair thinning or hair loss (alopecia), Abdominal pain, Tiredness, Vomiting, Low platelet count (thrombocytopenia),
VO: During my treatment with Verzenio, My oncologist encouraged me to try to do what I normally would do.
02:36
[Archival photos: Susan poses with son at a football game. Her husband and her son pose. Her daughter and friend pose with signs]
VO: When my son, it was a senior year and he's on the football team.
Caption: You should tell your doctor if you have any side effect that bothers you or does not go away. These are not all the possible side effects of Verzenio.
02:42
[Archival photos: Susan’s son and friends on the field after game]
VO: We went to every one of his games, whether they were home or away. So these were long days and I was concerned at first. I wasn't going to be able to do that and my doctor did.
Caption: For more information, you should ask your doctor or pharmacist.
02:51
[Susan talks to camera]
VO: That was one thing that she encouraged.
02:54
[Susan stands in front of a wall of photos, looks at them, then hangs up a photo of the group of women on a beach]
VO: I do like to travel and I was worried, is that something that was going to change now through this treatment? And I was able to get on a plane and I was able to still travel long distances. My friends, we love to go on a girls' trip, and that's been.
03:08
[Susan talks to camera]
VO: Something we just look forward to every year.
03:09
[The group of women sit on a couch, looking at a photo album]
VO: We were down at the beach.
Friend VO: It was like sunset.
03:12
[A page in the photo album is turned]
VO Susan: I'm so glad that we went last year.
03:14
[Susan talks to her friends]
VO:
I was very hesitant after surgery and thinking that I should just stay home.
03:18
[Archival photos: Susan on her beach trip]
VO: And I should skip the trip this year. And I was so glad you guys talked me into it. It's exactly what I needed.
03:25
[The women walk outside on a trail]
VO: Having my friends that I've been friends with for so long that we've been through so much together. Being a part of my journey just meant so much to me.
03:34
[Susan looks at the city skyline]
VO: And I want to do more things and see more places and be around for my children.
03:39
[Susan talks to camera]
VO: And I know that I'm doing all I can do.
03:48
Indication & Safety Summary:
VO + Caption: Verzenio is used to treat certain types of breast cancer known as HR+, HER2-negative, hormone receptor positive human epidermal growth factor receptor two negative breast cancer. It is a medicine you can take if you have no positive early breast cancer that has a high risk of coming back as determined by your healthcare provider. Verzenio is given along with hormonal therapy to women and men. It is not known if Verzenio is safe and effective in children.
04:14
VO + Caption: Warnings. Verzenio may cause serious side effects, including diarrhea is common with Verzenio, may sometimes be severe, and may cause dehydration or infection. The most common time to develop diarrhea is during the first month of Verzenio treatment. If you develop diarrhea during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, stop your treatment or decrease your dose. If you have any loose stools, start taking an anti-diarrheal medicine such as loperamide, drink more fluids, and tell your healthcare provider right away.
04:48
VO + Caption: Low white blood cell counts, neutropenia are common with Verzenio and may cause serious infections that can lead to death. Your healthcare provider should check your white blood cell counts before and during treatment. If you develop low white blood cell counts during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose or wait before starting your next month of treatment. Tell your healthcare provider right away if you have signs and symptoms of low white blood cell counts or infections, such as fever and chills.
05:18
VO + Caption: Verzenio may cause severe or life-threatening inflammation, swelling of the lungs during treatment that can lead to death. If you develop lung problems during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose, or stop your treatment. Tell your healthcare provider right away if you have any new or worsening symptoms, including trouble breathing or shortness of breath, cough with or without mucus, chest pain.
05:43
VO + Caption: Verzenio can cause serious liver problems. Your healthcare provider should do blood tests to check your liver before and during treatment. If you develop liver problems during treatment with Verzenio, your healthcare provider may reduce your dose or stop your treatment. Tell your healthcare provider right away if you have any of the following signs and symptoms of liver problems: Feeling very tired, loss of appetite, pain in the upper right side of your stomach area, abdomen, bleeding or bruising more easily than normal. Verzenio may cause blood clots in your veins or in the arteries of your lungs. Verzenio may cause serious blood clots that have led to death. If you develop blood clots during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it. Tell your healthcare provider right away if you have any of the following signs and symptoms of a blood clot: Pain or swelling in your arms or legs, fast breathing, shortness of breath, fast heart rate, chest pain.
06:38
VO + Caption: Verzenio can harm your unborn baby. Use effective birth control contraception during treatment and for three weeks after the last dose of Verzenio, and do not breastfeed during treatment with Verzenio and for at least three weeks after your last dose. Verzenio may affect the ability of males to father a child. Common side effects. The most common side effects of Verzenio include nausea, abdominal pain, infections, low red blood cell counts, anemia, decreased appetite, headache, hair thinning or hair loss, alopecia, tiredness, low white blood cell counts, leukopenia, vomiting, low platelet counts, thrombocytopenia. These are not all the possible side effects of Verzenio. Tell your healthcare provider if you have any side effects. You can report side effects at 1-800-FDA-1088, or www.fda.gov/medwatch.
07:37
VO + Caption: Before using. Before you use Verzenio, tell your healthcare provider about all your medical conditions, including if you have fever, chills, or other signs of infection, if you have a history of blood clots in your veins, have lung or breathing problems, have liver or kidney problems, if you are pregnant, plan to become pregnant or are breastfeeding, about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Especially tell your healthcare provider if you take a medicine that contains ketoconazole.
08:08
VO + Caption: How to take. Take Verzenio exactly as your healthcare provider tells you. Your healthcare provider may change your dose if needed. Do not stop taking Verzenio or change the dose without talking to your healthcare provider. Verzenio may be taken with or without food. Swallow Verzenio tablets whole. Do not chew, crush, or split the tablets before swallowing. Do not take Verzenio tablets if they're broken, cracked, or damaged. Take your doses of Verzenio at about the same time every day. If you vomit or miss a dose of Verzenio, take your next dose at your regular time. Do not take two doses at the same time to make up for the missed dose.
08:48
VO + Caption: What to avoid during treatment. Avoid taking ketoconazole during treatment with Verzenio. Tell your healthcare provider if you take a medicine that contains ketoconazole. Avoid grapefruit and products that contain grapefruit during treatment with Verzenio. Grapefruit may increase the amount of Verzenio in your blood.
09:06
VO + Caption: Learn more. Verzenio is a prescription medicine. For more information call 1-800-545-5979, or go to www.verzenio.com.This summary provides basic information about Verzenio but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Verzenio and how to take it. Your healthcare provider is the best person to help you decide if Verzenio is right for you. Verzenio is a registered trademark owned or licensed by Eli Lilly & Company, its subsidiaries or affiliates.
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